{"id":350,"date":"2020-11-19T08:48:49","date_gmt":"2020-11-19T08:48:49","guid":{"rendered":"https:\/\/egaltube.com\/en\/?p=350"},"modified":"2021-05-31T05:05:51","modified_gmt":"2021-05-30T23:05:51","slug":"polypill-could-cut-heart-attacks-strokes-up-to-40","status":"publish","type":"post","link":"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/","title":{"rendered":"Polypill could cut heart attacks & strokes up to 40%!"},"content":{"rendered":"

In what some researchers are calling a “transformational approach to preventing heart disease,” an inexpensive <\/span><\/span>Polypill<\/span><\/span>, along with an aspirin, cut heart attacks and strokes by up to 40%, according to<\/span><\/span> \u2018The International <\/span><\/span>Polycap<\/span><\/span> Study (TIPS-3)\u201d <\/span><\/span>published in the <\/span><\/span>New England Journal of <\/span><\/span>Medicine<\/span><\/span><\/a>.The<\/span><\/span> research was also presented at the<\/span><\/span> American Heart Association<\/span><\/span><\/a> Scientific Sessions on Friday, 13 November.<\/span><\/span><\/p>\n

For more than a decade, doctors have been testing whether the cheap, all-in-one combo pills could make it easier to prevent heart disease, the top killer worldwide. The results show their value \u2014 and not just for poor nations. <\/span><\/span>The study was funded by the <\/span><\/span>Wellcome<\/span><\/span> Trust, a British charity that supports research; <\/span><\/span>Cadila<\/span><\/span> Pharmaceuticals; and other public and private research organizations.<\/span><\/span><\/p>\n

A <\/span><\/span>Polypill<\/span><\/span> is a medicine that combines three different blood pressure medications (<\/span><\/span>atenolol<\/span><\/span>, <\/span><\/span>ramipril<\/span><\/span>, and the “water pill” hydrochlorothiazide) and a cholesterol-lowering <\/span><\/span>statin<\/span><\/span>medication <\/span><\/span>simvastatin<\/span><\/span>. These are all generic drugs. <\/span><\/span>Polypills<\/span><\/span>can be taken alone or with an aspirin.<\/span><\/span><\/p>\n

Researchers enrolled more than 5,700 <\/span><\/span>volunteers<\/span><\/span>, primarily in India and the Philippines plus <\/span><\/span>Colombia<\/span><\/span>,Canada<\/span><\/span>, Malaysia, Indonesia, Bangladesh, Tanzania and Tunisia. Eminence Associates for Social <\/span><\/span>Development,<\/span><\/span> a non-government health research based organization was the implementer of this research in Bangladesh. Public Health <\/span><\/span>reseacher<\/span><\/span> Dr <\/span><\/span>Shamim<\/span><\/span>Hyder<\/span><\/span> Talukder<\/span><\/span> lead the Bangladesh research team<\/span><\/span> and also Dr <\/span><\/span>Shahin<\/span><\/span> Akhter<\/span><\/span> coordinated this research<\/span><\/span> on behalf of Eminence. <\/span><\/span><\/p>\n

This study was to have run for five years and to have included 7,000 people, but drug delivery problems and the <\/span><\/span>coronavirus<\/span><\/span>pandemic forced researchers to cut it short. After just over four years on average, aspirin alone did not make a significant difference, and the <\/span><\/span>polypill<\/span><\/span> alone showed a trend toward modest benefit.<\/span><\/span><\/p>\n

Men had to be at least 50 years old and women at least 55 for this <\/span><\/span>study.<\/span><\/span>All<\/span><\/span> of the volunteers were considered to have a moderate risk for heart problems due to underlying conditions like diabetes or high blood <\/span><\/span>pressure.Researchers<\/span><\/span> followed <\/span><\/span>the volunteers for nearly five <\/span><\/span>years.The<\/span><\/span> volunteers were divided into groups and given either low-dose aspirin (75 milligrams)<\/span><\/span>,the<\/span><\/span>Polypill<\/span><\/span> alone, the <\/span><\/span>Polypill<\/span><\/span> plus aspirin or placebo pills. One group was assigned to get vitamin D, but those results are not available yet. Neither the participants nor their doctors knew who was taking what until the study ended.<\/span><\/span><\/p>\n

The <\/span><\/span>Polypill<\/span><\/span> with the aspirin reduced heart problems and deaths by 31% and came with minimal side effects. <\/span><\/span>About 1.5% more of the <\/span><\/span>polypill<\/span><\/span> users had dizziness or low blood pressure, but they could be switched to a lower dose if that happened<\/span><\/span>. Those who continued to take the pill without interruption show 40% reduced risk of heart <\/span><\/span>problems.Only<\/span><\/span> about 4% in the group that took the <\/span><\/span>Polypill<\/span><\/span> and aspirin had a heart problem like a stroke or heart attack or another heart problem tracked by this study or died, compared to the nearly 6% who did in the placebo group.<\/span><\/span><\/p>\n

“We could save millions of people from experiencing serious heart disease or stroke each year with effective use of the <\/span><\/span>Polypill<\/span><\/span> and aspirin,” said <\/span><\/span>SalimYusuf<\/span><\/span>, Principal Investigator for the study and a professor of medicine at<\/span><\/span> McMaster University<\/span><\/span><\/a> in Canada, in a news release.<\/span><\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

In what some researchers are calling a “transformational approach to preventing heart disease,” an inexpensive Polypill, along with an aspirin,<\/p>\n","protected":false},"author":1,"featured_media":434,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15,27,12],"tags":[],"yoast_head":"\nPolypill could cut heart attacks & strokes up to 40%! - eGal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Polypill could cut heart attacks & strokes up to 40%!\" \/>\n<meta property=\"og:description\" content=\"In what some researchers are calling a "transformational approach to preventing heart disease," an inexpensive Polypill, along with an aspirin, cut heart\" \/>\n<meta property=\"og:url\" content=\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\" \/>\n<meta property=\"og:site_name\" content=\"eGal\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/eGaLTube\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-19T08:48:49+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-05-30T23:05:51+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/egaltube.com\/en\/wp-content\/uploads\/2020\/11\/default_800_420.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"420\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"eGal\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@eGaLTube\" \/>\n<meta name=\"twitter:site\" content=\"@eGaLTube\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"eGal\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\"},\"author\":{\"name\":\"eGal\",\"@id\":\"https:\/\/egaltube.com\/en\/#\/schema\/person\/6dafd00f7a6f246750297ef4a60cce31\"},\"headline\":\"Polypill could cut heart attacks & strokes up to 40%!\",\"datePublished\":\"2020-11-19T08:48:49+00:00\",\"dateModified\":\"2021-05-30T23:05:51+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\"},\"wordCount\":528,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/egaltube.com\/en\/#organization\"},\"articleSection\":[\"Opinion\",\"Special\",\"Tips & Tricks\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\",\"url\":\"https:\/\/egaltube.com\/en\/polypill-could-cut-heart-attacks-strokes-up-to-40\/\",\"name\":\"Polypill could cut heart attacks & strokes up to 40%! 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